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Understanding the genetic causes of common childhood kidney disease

Understanding the genetic causes of common childhood kidney disease 05 February 2024 Dr Horia Stanescu from University College London has been awarded a research project grant of £220,000 to investigate the genetic causes of steroid-sensitive nephrotic syndrome (SSNS).  Why is steroid-sensitive nephrotic syndrome a problem? SSNS is the most common cause of kidney disease in…

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New study shows potential of gene therapy in nephrotic syndrome

New study shows potential of gene therapy in nephrotic syndrome 10 August 2023 In a new study published in Science Translational Medicine, researchers at the University of Bristol have shown that just one dose of gene therapy targeting cells in the kidney called podocytes has the potential to cure steroid-resistant nephrotic syndrome.  An innovative approach…

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Research gives new hope to patients with idiopathic nephrotic syndrome

Research gives new hope to patients with idiopathic nephrotic syndrome 18 April 2023 Professor Moin Saleem, University of Bristol New research by Professors Moin Saleem, Gavin Welsh and  their team at the University of Bristol, supported by Kidney Research UK, has provided important new clues into idiopathic nephrotic syndrome (INS) with exciting implications for improved…

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Investigating a novel treatment for nephrotic syndrome and diabetic nephropathy

Investigating a novel treatment for nephrotic syndrome and diabetic nephropathy 11 July 2022 Imagine being on a course of treatment and tolerating the many side effects for weeks only to find that the treatment has been futile. This is the scenario facing up to 20% of patients with steroid resistant nephrotic syndrome (NS). Steroids aren’t…

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Looking for ways to improve treatments for nephrotic syndrome

Looking for ways to improve treatments for nephrotic syndrome 04 July 2022 Professor Moin Saleem and his team at Bristol Renal are heavily focussed on improving treatments for nephrotic syndrome by looking at the specific cause of disease in each individual patient and tailoring treatment accordingly. To this end we have funded an exciting new…

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